SAG Analog (LowTox)
| Code | Size | Price |
|---|
| AG-CR1-3517-M001 | 1 mg | £200.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Compound 10c; 3,4-Dichloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide
Appearance:
White to light yellow solid.
CAS:
1401532-78-2
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light.
InChi:
InChI=1/C28H27Cl2N3OS/c1-31-21-8-10-22(11-9-21)33(17-18-4-2-5-20(16-18)19-12-14-32-15-13-19)28(34)27-26(30)25-23(29)6-3-7-24(25)35-27/h2-7,12-16,21-22,31H,8-11,17H2,1H3/t21-,22-
InChiKey:
OBYJCKCGYTYXFN-HZCBDIJEBZ
Long Description:
Chemical. CAS: 1401532-78-2. Formula: C28H27Cl2N3OS (trans-isomer). MW: 524.5. Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.
MDL:
N/A
Molecular Formula:
C28H27Cl2N3OS (trans-isomer)
Molecular Weight:
524.5
Package Type:
Vial
Product Description:
Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.
Purity:
>98% (NMR)
SMILES:
[H][C@@]1(CC[C@@]([H])(CC1)N(CC1=CC=CC(=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=C(Cl)C=CC=C2S1)NC
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
References
Potent small molecule Hedgehog agonists induce VEGF expression in vitro: K. Seifert, et al.; Bioorg. Med. Chem. 20, 6465 (2012)