Pikromycin
| Code | Size | Price |
|---|
| BVT-0400-M001 | 1 mg | £95.00 |
Quantity:
| BVT-0400-M005 | 5 mg | £265.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Picromycin; Amaromycin; Antibiotic B 62169A; Albomycetin
Appearance:
White crystalline solid.
CAS:
19721-56-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C28H47NO8/c1-10-22-28(7,34)12-11-21(30)15(2)13-16(3)25(18(5)23(31)19(6)26(33)36-22)37-27-24(32)20(29(8)9)14-17(4)35-27/h11-12,15-20,22,24-25,27,32,34H,10,13-14H2,1-9H3/b12-11+/t15-,16+,17-,18+,19-,20?,22-,24-,25+,27+,28+/m1/s1
InChiKey:
UZQBOFAUUTZOQE-AKYJXTIJSA-N
Long Description:
Chemical. CAS: 19721-56-3. Formula: C28H47NO8. MW: 525.7. Isolated from Streptomyces sp. Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.
MDL:
MFCD00046974
Molecular Formula:
C28H47NO8
Molecular Weight:
525.7
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2OC(C)C[C@H](C2O)N(C)C)[C@@H](C)C[C@@H](C)C(=O)C=C[C@]1(C)O
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Isolated from Streptomyces sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Pikromycin, ein neues Antibiotikum aus Actinomyceten: H. Brockmann & W. Henkel; Naturwissenschaften 37, 138 (1950) | Pikromycin, ein bitter schmeckendes antibioticum aus Actinomyceten: H. Brockmann & W. Henkel; Chem. Ber. 84, 284 (1951) | The crystal and molecular structure of Pikromycin: A. Furusaki, et al.; Bull. Chem. Soc. Jpn. 55, 59 (1982) | Albocycline- and carbomycin-type macrolides, inhibitors of human prylol endopeptidases: C. Christner, et al.; J. Antibiot. 51, 368 (1998) | The Methymycin/pikromycin pathway: A model for metabolic diversity in natural product biosynthesis: J. D. Kittendorf & D. H. Sherman; Bioorg. Med. Chem. 17, 2137 (2009) | Total synthesis of Pikromycin: H.-S. Oh & H.-Y. Kang; J. Org. Chem. 77, 1125 (2012)
Related Products
| Product Name | Product Code | Supplier | Chaetoviridin A | BVT-0419 | Bioviotica | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|