anti-Podoplanin (mouse) mAb (RTD4E10)
| Code | Size | Price |
|---|
| AG-20T-0101-C100 | 100 ug | £400.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Clonality: Monoclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
-20°C
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Glycoprotein 36; PA2.26 Antigen; Aggrus
EClass:
32160000
Form (Short):
solid
Formulation:
Lyophilized.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Murine thymic stromal cell line.
Long Description:
Monoclonal Antibody. Recognizes mouse podoplanin. Does not cross-react with human podoplanin. Isotype: Hamster IgG. Clone: RTD4E10. Applications: ELISA, IHC, IP, WB. Lyophilized. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
NCBI, Uniprot Number:
N/A
Package Type:
Plastic Vial
Product Description:
Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
Purity:
Protein G purified.
Source / Host:
Synthetic.
Specificity:
Recognizes mouse podoplanin. Does not cross-react with human podoplanin.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.
References
Mouse lungs contains endothelial progenitors with high capacity to form blood and lymphatic vessels: J. Schniedermann, et al.; BMC Cell Biology 11, 1471 (2010)