VEGF-C (rat) (rec.) (His)
| Code | Size | Price |
|---|
| AG-40T-0048-C005 | 5 ug | £165.00 |
Quantity:
| AG-40T-0048-C020 | 20 ug | £340.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Bovine (Cattle)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Vascular Endothelial Growth Factor C; VRP; Flt4-L
EClass:
32160000
Form (Short):
liquid
Formulation:
Lyophilized.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. Rat VEGF-C (127aa) is fused at the C-terminus to a His-tag. Source: Sf9 cells. Lyophilized. Purity: >90% (SDS-PAGE). VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
Molecular Weight:
~15-20kDa
NCBI, Uniprot Number:
O35757
Package Type:
Plastic Vial
Product Description:
VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
Purity:
>90% (SDS-PAGE)
Sequence:
Rat VEGF-C (127aa) is fused at the C-terminus to a His-tag.
Source / Host:
Sf9 cells
TAGs:
His
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.
References
Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model: M. Yashiro, et al.; Br. J. Cancer 101, 1100 (2009) | Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis: CF. Calvo, et al.; Genes Dev. 25, 831 (2011)