Neoxaline
Product Code: AG-CN2-0154
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0154-M001 | 1 mg | £200.00 |
Quantity:
| AG-CN2-0154-M005 | 5 mg | £770.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Nedoxaline; BRN 5669473
Appearance:
White solid.
CAS:
71812-10-7
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light.Protect from moisture.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C23H25N5O4/c1-5-21(2,3)22-11-18(29)20(31)27-17(10-14-12-24-13-25-14)19(30)26-23(22,27)28(32-4)16-9-7-6-8-15(16)22/h5-10,12-13,18,29H,1,11H2,2-4H3,(H,24,25)(H,26,30)/b17-10+
InChiKey:
HHLNXXASUKFCCX-LICLKQGHSA-N
Long Description:
Chemical. CAS: 71812-10-7. Formula: C23H25N5O4. MW: 435.5. Isolated from Aspergillus japonicus Fg-551. Antimitotic. Cell cycle inhibitor at the G2/M phase. Antiproliferative. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation. Mycotoxin.
MDL:
MFCD01720345
Molecular Formula:
C23H25N5O4
Molecular Weight:
435.5
Package Type:
Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Antimitotic. Cell cycle inhibitor at the G2/M phase [3, 4]. Antiproliferative [3]. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation [1, 2]. Mycotoxin [1].
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
CON1C2=C(C=CC=C2)C2(CC(O)C(=O)N3C(=CC4=CNC=N4)C(=O)NC123)C(C)(C)C=C
Solubility Chemicals:
Soluble in methanol, chloroform or ethyl acetate. Insoluble in water or hexane.
Source / Host:
Isolated from Aspergillus japonicus Fg-551.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Neoxaline, a new alkaloid produced by Aspergillus japonicus. Production, isolation and properties: A. Hirano, et al.; J. Antibiot. 32, 781 (1979) | Oxaline and Neoxaline: Y. Konda, et al.; Chem. Pharm. Bull. 28, 2987 (1980) | Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization.: Y. Koizumi, et al.; Biochim. Biophys. Acta 1693, 47 (2004) | Efficient total synthesis of novel bioactive microbial metabolites: T. Sunazuka, et al.; Acc. Chem. Res. 41, 302 (2008)
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