NG 012

AdipoGen Life Sciences
Product Code: AG-CN2-0155
CodeSizePrice
AG-CN2-0155-M0011 mg£105.00
Quantity:
AG-CN2-0155-M0055 mg£390.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
BK223A; 15G256alpha; 32-Hydroxy-orbuticin
Appearance:
Pale white solid.
CAS:
141731-76-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C32H38O15/c1-15-5-19-9-21(34)11-24(36)29(19)32(42)46-18(4)8-27(39)47-23(14-33)13-28(40)44-16(2)6-20-10-22(35)12-25(37)30(20)31(41)45-17(3)7-26(38)43-15/h9-12,15-18,23,33-37H,5-8,13-14H2,1-4H3/t15-,16-,17-,18-,23+/m1/s1
InChiKey:
QFILNQIVBJLREP-RZOYPLJHSA-N
Long Description:
Chemical. CAS: 141731-76-2. Formula: C32H38O15. MW: 662.7. Isolated from Penicillium sp. FKI-5387. Antibiotic. Antifungal. Nerve growth factor (NGF) potentiator.
MDL:
MFCD23160330
Molecular Formula:
C32H38O15
Molecular Weight:
662.7
Package Type:
Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Antibiotic. Mycotoxin. Very weak cytotoxic activity. Antifungal. Inhibits cell wall biosynthesis. Nerve growth factor (NGF) potentiator.
Purity:
>95% (TLC)
Signal word:
Warning
SMILES:
C[C@@H]1CC2=C(C(O)=CC(O)=C2)C(=O)O[C@H](C)CC(=O)O[C@H](CO)CC(=O)O[C@H](C)CC2=C(C(O)=CC(O)=C2)C(=O)O[C@H](C)CC(=O)O1
Solubility Chemicals:
Soluble in methanol, ethanol, ethyl acetate, chloroform, acetonitrile or acetone. Insoluble in water or hexane.
Source / Host:
Isolated from Penicillium sp. FKI-5387.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

NG 011 and NG 012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties: M. Ito, et al.; J. Antibiot. 45, 1559 (1992) | NG 011 and NG 012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012: M. Ito, et al.; J. Antibiot. 45, 1566 (1992) | Antifungal macrocyclic polylactones from Penicillium verruculosum: J. Breinholt, et al.; J. Antibiot. 46, 1101 (1993) | Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256: G. Schlingmann, et al.; Tetrahedron 58, 6825 (2002) | Biomimetic Synthesis of Resorcylate Natural Products Utilizing Late Stage Aromatization: Concise Total Syntheses of the Marine Antifungal Agents 15G256iota and 15G256beta: I. Navarro, et al.; JACS 130, 10293 (2008) | New Cytotoxic Metabolites from the Marine-Derived Fungus Penicillium sp. ZLN29: H. Gao, et al.; Helv. Chim. Acta 96, 514 (2013) | New polyesters from Talaromyces flavus: J.-W. He, et al.; Tetrahedr. 70, 4425 (2014)

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