GPR15 Antibody

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ProSci
Product Code: PSI-2101
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-2101-0.02mg0.02mg£150.00
Quantity:
PSI-2101-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)

Images

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Western blot analysis of GPR15 in human spleen lysate with GPR15 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunocytochemistry of GPR15 in A431 cells with GPR15 antibody at 5 μg/ml.
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Western blot analysis of GPR15 in human spleen lysate with GPR15 antibody at (A) 0.5 and (B) 1 μg/mL.
Immunocytochemistry of GPR15 in A431 cells with GPR15 antibody at 5 μg/ml.

Documents

Further Information

Additional Names:
GPR15 Antibody: BOB
Application Note:
GPR15 antibody can be used for detection of GPR15 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
Background:
GPR15 Antibody: Human immunodeficiency virus (HIV) and related viruses require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four other molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. GPR15, also known as BOB, is a G protein-coupled receptor that serves as coreceptor for the simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1.
Background References:
  • Heiber M, Marchese A, Nguyen T, et al. A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Genomics 1996; 32:462-5
  • Deng HK, Unutmaz D, KewalRamani VN, et al. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 1997; 388:296-300
  • Farzan M, Choe H, Martin K, et al. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J. Exp. Med. 1997;186:405-11.
Buffer:
GPR15 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GPR15 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human GPR15.

The immunogen is located within the first 50 amino acids of GPR15.
NCBI Gene ID #:
2838
NCBI Official Name:
G protein-coupled receptor 15
NCBI Official Symbol:
GPR15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 40 kDa

Observed: 49 kDa
Protein Accession #:
U34806
Protein GI Number:
1171145
Purification:
GPR15 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis,Chemokines & Cytokines,Infectious Disease
Swissprot #:
U34806
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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