CARD9 Antibody
| Code | Size | Price |
|---|
| PSI-2515-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-2515-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
CARD9 Antibody: CANDF2, hCARD9, Caspase recruitment domain-containing protein 9
Application Note:
CARD9 antibody can be used for detection of CARD9 by Western blot at 2.5 μg/mL. A band at approximately 59 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
Background:
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κB. CARD9 is an upstream activator of BCL-10 and NF-κB signaling.
Background References:
- Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κ B. J Biol Chem. 2000;275(52):41082-6. (RD0202)
Buffer:
CARD9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (88%), Rat: (82%)
Immunogen:
CARD9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CARD9.
The immunogen is located within the last 50 amino acids of CARD9.
The immunogen is located within the last 50 amino acids of CARD9.
NCBI Gene ID #:
64170
NCBI Official Name:
caspase recruitment domain family, member 9
NCBI Official Symbol:
CARD9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
AF311287
Protein GI Number:
11066983
Purification:
CARD9 Antibody is DEAE purified.
Research Area:
Apoptosis
Swissprot #:
Q9H257
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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