FABP7 Antibody
| Code | Size | Price |
|---|
| PSI-4259-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4259-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
FABP7 Antibody: MRG, BLBP, FABPB, B-FABP, MRG, Fatty acid-binding protein, brain, Brain lipid-binding protein
Application Note:
FABP7 antibody can be used for detection of FABP7 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
FABP7 Antibody: FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
Background References:
- Shimizu F, Watanabe TK, Shinomiya H, et al. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim. Biophys. Acta1997; 1354:24-8.
- Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet.2006; 47:39-48.
- Arai Y, Funatsu N, Numayama-Tsuruta K, et al. Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.2005; 25:9752-61.
- Goto Y, Matsuzaki Y, Kurihara S, et al. A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.2006; 66:4443-9.
Buffer:
FABP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (94%), Rat: (94%), Mouse: (88%)
Immunogen:
FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.
The immunogen is located within the last 50 amino acids of FABP7.
The immunogen is located within the last 50 amino acids of FABP7.
NCBI Gene ID #:
2173
NCBI Official Name:
fatty acid binding protein 7, brain
NCBI Official Symbol:
FABP7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW48166
Protein GI Number:
119568551
Purification:
FABP7 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
O15540
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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