Rift Valley Fever Virus Antibody
| Code | Size | Price |
|---|
| PSI-4519-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4519-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Documents
Further Information
Additional Names:
Rift Valley Fever Virus Antibody: Envelope glycoprotein, M polyprotein, GP
Application Note:
RVF virus antibody can detect 10ng RVF virus peptide in ELISA at 1 μg/mL.
Background:
Rift Valley Fever Virus Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes. During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity. The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins. This RVF virus antibody was derived from a peptide sequence near the center of the polyprotein precursor translated from the M segment. It will therefore detect both the precursor and the Glycoprotein G1.
Background References:
- Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.
- Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
- Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology1991; 180:738-53.
Buffer:
Rift Valley Fever Virus Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
RVF virus antibody was raised against a 20 amino acid synthetic peptide near the center of the RVF virus.
The immunogen is located within amino acids 360 - 410 of Rift Valley Fever Virus.
The immunogen is located within amino acids 360 - 410 of Rift Valley Fever Virus.
NCBI Gene ID #:
9538296
NCBI Official Name:
Envelope glycoprotein
NCBI Official Symbol:
RVFV_sM_gp1
NCBI Organism:
Rift Valley fever virus
Physical State:
Liquid
Protein Accession #:
P03518
Protein GI Number:
1174956
Purification:
Rift Valley Fever Virus Antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
P03518
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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