BAP3 Antibody
| Code | Size | Price |
|---|
| PSI-4503-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4503-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
BAP3 Antibody: BAP3, KIAA0734, BAI1-associated protein 3, BAP3
Application Note:
BAP3 antibody can be used for the detection of BAP3 by Western blot at 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
BAP3 Antibody: BRAL1 is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.
Background References:
- Shiratsuchi T, Oda K, Nishimori H, et al. Cloning and characterization of BAP (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochem. Biophys. Res. Comm.1998; 251:158-65.
- Palmer RE, Lee SB, Wong JC, et al. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis. Cancer Cell2002; 2:497-505.
Buffer:
BAP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BAP3 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human BAP3.
The immunogen is located within the first 50 amino acids of BAP3.
The immunogen is located within the first 50 amino acids of BAP3.
NCBI Gene ID #:
8938
NCBI Official Name:
BAI-associated protein 3
NCBI Official Symbol:
BAIAP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
BAA34710
Protein GI Number:
3929917
Purification:
BAP3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
O94812
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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