Unc93a Antibody
| Code | Size | Price |
|---|
| PSI-4551-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4551-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
Unc93a Antibody: Unc-93A, dJ366N23.1, dJ366N23.2, Protein unc-93 homolog A, HmUnc-93A
Application Note:
Unc93a antibody can be used for the detection of Unc93a by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
Unc93a Antibody: Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.
Background References:
- Liu Y, Dodds P, Emilion G, et al. The human homolog of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. BioMed Central Genetics2002; 3:20.
- Massey DC and Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy2007; 3:649-51.
Buffer:
Unc93a Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Unc93a antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human Unc93a.
The immunogen is located within the last 50 amino acids of Unc93a.
The immunogen is located within the last 50 amino acids of Unc93a.
NCBI Gene ID #:
54346
NCBI Official Name:
unc-93 homolog A (C. elegans)
NCBI Official Symbol:
UNC93A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
AAH99718
Protein GI Number:
71043465
Purification:
Unc93a Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.
Swissprot #:
Q86WB7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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