RGP1 Antibody
| Code | Size | Price |
|---|
| PSI-4569-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4569-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
RGP1 Antibody: KIAA0258, KIAA0258, Retrograde Golgi transport protein RGP1 homolog
Application Note:
RGP1 antibody can be used for detection of RGP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
RGP1 Antibody: Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, a protein that forms a tight complex with RIC1. This complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 is localized to the Golgi and is thought to be a potential Golgi recycling factor. Rgp1 yeast mutants exhibit defects in retrograde trafficking similar to those seen in yeast with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells to that seen in yeast.
Background References:
- Siniossoglou S, Peak-Chew SY, and Pelham HRB. Ric1p and Rgp1 form a complex that catalyzes nucleotide exchange on Ypt6p. EMBO J.2000; 19:4885-94.
- Panek HR, Conibear E, Bryan JD, et al. Identification of Rgp1, a novel Golgi recycling factor, as a protein required for efficient localization of yeast casein kinase 1 to the plasma membrane. J. Cell Sci.113:4545-55.
Buffer:
RGP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen:
RGP1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of the human RGP1.
The immunogen is located within amino acids 50 - 100 of RGP1.
The immunogen is located within amino acids 50 - 100 of RGP1.
NCBI Gene ID #:
9827
NCBI Official Name:
RGP1 retrograde golgi transport homolog (S. cerevisiae)
NCBI Official Symbol:
RGP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001073965
Protein GI Number:
122937426
Purification:
RGP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q92546
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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