UROP11 Antibody
| Code | Size | Price |
|---|
| PSI-4615-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4615-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
UROP11 Antibody: X11, Mint, Mint1, Lin-10, Urop11, X11alpha, 6430513E09Rik, X11, Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Mint-1
Application Note:
UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.
Background References:
- Verlaeten O, Casery C, Cavagna S, et al. Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity. J. Mol. Endocrinol.2007; 38:3-17.
Buffer:
UROP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
UROP11 antibody was raised against a 12 amino acid synthetic peptide near the center of the mouse UROP11.
The immunogen is located within the first 50 amino acids of UROP11.
The immunogen is located within the first 50 amino acids of UROP11.
NCBI Gene ID #:
319924
NCBI Official Name:
amyloid beta (A4) precursor protein binding, family A, member 1
NCBI Official Symbol:
Apba1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
CAD90042
Protein GI Number:
30348608
Purification:
UROP11 Antibody is affinity chromatography purified via peptide column.
Research Area:
Obesity
Swissprot #:
B2RUJ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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