GRTP1 Antibody
| Code | Size | Price |
|---|
| PSI-4589-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4589-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
GRTP1 Antibody: TBC1D6, TBC1D6, Growth hormone-regulated TBC protein 1, TBC1 domain family member 6
Application Note:
GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
GRTP1 Antibody: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
Background References:
- Lu C, Kasik J, Stephan DA, et al. Grtp1, a novel gene regulated by growth hormone. Endocriniology2001; 142:4568-71.
- Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.
Buffer:
GRTP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GRTP1 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human GRTP1.
The immunogen is located within the first 50 amino acids of GRTP1.
The immunogen is located within the first 50 amino acids of GRTP1.
NCBI Gene ID #:
79774
NCBI Official Name:
growth hormone regulated TBC protein 1
NCBI Official Symbol:
GRTP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAX09206
Protein GI Number:
119629611
Purification:
GRTP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q5TC63
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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