NUP155 Antibody
| Code | Size | Price |
|---|
| PSI-4703-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4703-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
NUP155 Antibody: N155, KIAA0791, Nuclear pore complex protein Nup155, 155 kDa nucleoporin
Application Note:
NUP155 antibody can be used for detection of NUP155 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
NUP155 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.
Background References:
- Tran EJ and Wente SR. Dynamic nuclear pore complex: life on the edge. Cell2006; 125:1041-53.
- Radu A, Blobel G and Wozniak RW. Nup155 is a novel nuclear pore complex protein that contains neither repetitive sequence motifs nor reacts with WGA. J. Cell Biol.1993; 121:1-9.
- Hawryluk-Gara LA, Shibuya EK, and Wozniak RW. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol. Biol. Cell2005; 16:2382-94.
- Rayala HJ, Kendirgi F, Barry DM, et al. The mRNA export factor Gle1 interacts with the nuclear pore complex protein Nup155. Mol. Cell Proteomics2004; 3:145-55.
Buffer:
NUP155 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat: (100%)
Immunogen:
NUP155 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NUP155.
The immunogen is located within the last 50 amino acids of NUP155.
The immunogen is located within the last 50 amino acids of NUP155.
NCBI Gene ID #:
9631
NCBI Official Name:
nucleoporin 155kDa
NCBI Official Symbol:
NUP155
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_705618
Protein GI Number:
24430149
Purification:
NUP155 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
O75694
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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