RGPD5 Antibody
| Code | Size | Price |
|---|
| PSI-4587-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4587-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
RGPD5 Antibody: BS63, RGP5, BS-63, HEL161, RANBP2L1, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, Sperm membrane protein BS-63, RanBP2L1
Application Note:
RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
Background References:
- Nothwang HG, Rensing C, Kubler M, et al. Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on chromosome 2q11-q12. Genomics1998; 47:383-92.
- Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.
- Wang LF, Zhu HD, Miao SY, et al. Molecular cloning and characterization of a novel testis-specific nucleoporin-related gene. Arch. Androl.1999; 42:71-84.
Buffer:
RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
RGPD5 antibody was raised against a 23 amino acid synthetic peptide from near the center of human RGPD5.
The immunogen is located within amino acids 1130 - 1180 of RGPD5.
The immunogen is located within amino acids 1130 - 1180 of RGPD5.
NCBI Gene ID #:
84220
NCBI Official Name:
RANBP2-like and GRIP domain containing 5
NCBI Official Symbol:
RGPD5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_005045
Protein GI Number:
83267877
Purification:
RGPD5 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q99666
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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