OVGP1 Antibody

ProSci
Product Code: PSI-4763
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-4763-0.02mg0.02mg£150.00
Quantity:
PSI-4763-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

1 / 4
Western blot analysis of OVGP1 in human placenta tissue lysate with OVGP1 antibody at 1 μg/mL.
2 / 4
Immunocytochemistry of OVGP1 in 293 cells with OVGP1L antibody at 2.5 μg/mL.
3 / 4
Immunofluorescence of OVGP1 in 293 cells with OVGP1 antibody at 2.5 μg/mL.
4 / 4
Immunofluorescence of OVGP1 in Hek293 cells with OVGP1 antibody at 20 μg/mL.<br><br>Green: OVGP1 Antibody (4763) <br> Blue: DAPI staining

Western blot analysis of OVGP1 in human placenta tissue lysate with OVGP1 antibody at 1 μg/mL.
Immunocytochemistry of OVGP1 in 293 cells with OVGP1L antibody at 2.5 μg/mL.
Immunofluorescence of OVGP1 in 293 cells with OVGP1 antibody at 2.5 μg/mL.
Immunofluorescence of OVGP1 in Hek293 cells with OVGP1 antibody at 20 μg/mL.<br><br>Green: OVGP1 Antibody (4763) <br> Blue: DAPI staining

Further Information

Additional Names:
OVGP1 Antibody: EGP, OGP, MUC9, CHIT5, Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein
Application Note:
OVGP1 antibody can be used for the detection of OVGP1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.

Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
OVGP1 Antibody: Oviductins belong to a family of glycoproteins that have been suggested to play several roles during the early processes of reproduction. OVGP1 is a large carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites within threonine, serine, and proline-rich tandem repeats. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. At least two isoforms of OVGP are known to exist.
Background References:
  • Buhi WC. Characterization and biological roles of oviduct-specific, oestrogen-dependent glycoprotein. Reproduction123:355-62.
  • Arias EB, Verhage HG and Jaffe RC. Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein. Biol. Reprod.1994; 51:685-94.
Buffer:
OVGP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Sheep: (94%), Bovine: (94%), Pig: (79%)
Immunogen:
OVGP1 antibody was raised against an 18 amino acid synthetic peptide from near the amino terminus of human OVGP1.

The immunogen is located within amino acids 60 - 110 of OVGP1.
NCBI Gene ID #:
5016
NCBI Official Name:
oviductal glycoprotein 1, 120kDa
NCBI Official Symbol:
OVGP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 75 kDa

Observed: Due to extensive post-translational modification, OVGP1 migrates at ~140 kDa in SDS-PAGE.
Protein Accession #:
NP_002548
Protein GI Number:
58386720
Purification:
OVGP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q12889
User NOte:
Optimal dilutions for each application to be determined by the researcher.

Related Products

Product NameProduct CodeSupplier 
OVGP1 PeptidePSI-4763PProSci Summary Details