ZBTB1 Antibody

ProSci
Product Code: PSI-4951
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-4951-0.02mg0.02mg£150.00
Quantity:
PSI-4951-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of ZBTB1 in HepG2 lysate with ZBTB1 antibody at (A) 1 and (B) 2 μg/mL.
2 / 2
Immunohistochemistry of ZBTB1 in mouse brain tissue with ZBTB1 antibody at 2.5 μg/mL.

Western blot analysis of ZBTB1 in HepG2 lysate with ZBTB1 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of ZBTB1 in mouse brain tissue with ZBTB1 antibody at 2.5 μg/mL.

Further Information

Additional Names:
ZBTB1 Antibody: ZNF909, KIAA0997, Zinc finger and BTB domain-containing protein 1
Application Note:
ZBTB1 antibody can be used for detection of ZBTB1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
ZBTB1 Antibody: ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration.
Background References:
  • Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.
  • Li Z, Stonehuerner J, Devlin RB, et al. Discrimination of Vanadium from Zinc using gene profiling in human bronchial epithelial cells. Envir. Health Perspect.2005; 113:1747-54.
  • Zhang H, Morrison MA, Dewan A, et al. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med. Genet.2008; 9:51.
Buffer:
ZBTB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZBTB1 antibody was raised against a 14 amino acid synthetic peptide near the center of human ZBTB1.

The immunogen is located within amino acids 260 - 310 of ZBTB1.
NCBI Gene ID #:
22890
NCBI Official Name:
zinc finger and BTB domain containing 1
NCBI Official Symbol:
ZBTB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
AAH50719
Protein GI Number:
29792103
Purification:
ZBTB1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least two isoforms of ZBTB1 are known to exist. This ZBTB1 antibody will not cross-react with ZBTB2.
Swissprot #:
Q9Y2K1
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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