NIPSNAP2 Antibody
| Code | Size | Price |
|---|
| PSI-4943-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4943-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
NIPSNAP2 Antibody: NIPSNAP2, NIPSNAP2, Protein NipSnap homolog 2, Glioblastoma-amplified sequence, NipSnap2
Application Note:
NIPSNAP2 antibody can be used for detection of NIPSNAP2 by Western blot at 0.5 and 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
NIPSNAP2 Antibody: The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Background References:
- Seroussi E, Pan HQ, Kedra D, et al. Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Gene1998; 212:13-20.
- Wang X-Y, Smith DI, Liu W, et al. GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR. Genomics1998; 49:448-51.
Buffer:
NIPSNAP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NIPSNAP2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NIPSNAP2.
The immunogen is located within the first 50 amino acids of NIPSNAP2.
The immunogen is located within the first 50 amino acids of NIPSNAP2.
NCBI Gene ID #:
2631
NCBI Official Name:
glioblastoma amplified sequence
NCBI Official Symbol:
GBAS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
O75323
Protein GI Number:
17380133
Purification:
NIPSNAP2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
O75323
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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