OCC-1 Antibody
| Code | Size | Price |
|---|
| PSI-4987-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-4987-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
OCC-1 Antibody: AGD3, OCC1, OCC-1, C12orf75, Overexpressed in colon carcinoma 1 protein, AGD3
Application Note:
OCC-1 antibody can be used for detection of OCC-1 by Western blot at 2 - 4 μg/mL. In vitro transcription and translation of the OCC-1 cDNA yields polypeptides less than 9 kDa. Despite this, OCC-1 from cell lines is detected at ~28 kDa in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
OCC-1 Antibody: OCC-1 (Overexpressed in colon carcinoma-1) was initially identified as a novel human cDNA overexpressed in a colon carcinoma cell line. Elevated levels of OCC-1 mRNA were observed in three of eight colon carcinomas, suggesting that OCC-1 may be a hallmark of only a subset of colon carcinomas. It is highly expressed in skeletal muscle, kidney, placenta, and pancreas tissues, with low to no expression in heart, brain, lung and liver tissues. At least two different OCC-1 mRNA species are known to exist.
Background References:
- Pibouin L, Villaudy J, Ferbus D, et al. Cloning of the mRNA of overexpression in colon-carcinoma-1: a sequence overexpressed in a subset of colon carcinomas. Cancer Genet. Cytogenet.2002; 133:55-60.
Buffer:
OCC-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
OCC-1 antibody was raised against a 7 amino acid synthetic peptide near the carboxy terminus of human OCC-1.
The immunogen is located within the last 50 amino acids of OCC-1.
The immunogen is located within the last 50 amino acids of OCC-1.
NCBI Gene ID #:
387882
NCBI Official Name:
chromosome 12 open reading frame 75
NCBI Official Symbol:
C12orf75
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
AAH61920
Protein GI Number:
112180576
Purification:
OCC-1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer
Swissprot #:
Q8TAD7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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