ZIP11 Antibody

ProSci
Product Code: PSI-5001
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5001-0.02mg0.02mg£150.00
Quantity:
PSI-5001-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

1 / 2
Western blot analysis of ZIP11 in mouse kidney tissue lysate with ZIP11 antibody at (A) 1 and (B) 2 μg/mL.
2 / 2
Immunohistochemistry of ZIP11 in mouse kidney tissue with ZIP11 antibody at 2.5 μg/mL.

Western blot analysis of ZIP11 in mouse kidney tissue lysate with ZIP11 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of ZIP11 in mouse kidney tissue with ZIP11 antibody at 2.5 μg/mL.

Further Information

Additional Names:
ZIP11 Antibody: ZIP11, C17orf26, ZIP11, Zinc transporter ZIP11, Solute carrier family 39 member 11, ZIP-11
Application Note:
ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.
Background References:
  • Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
  • Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
  • Liuzzi JP and Cousins RJ. Mammalian zinc transporters. Annu. Rev. Nutr.2004; 24:151-72.
Buffer:
ZIP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (86%)
Immunogen:
ZIP11 antibody was raised against a 15 amino acid synthetic peptide near the center of the human ZIP11.

The immunogen is located within amino acids 130 - 180 of ZIP11.
NCBI Gene ID #:
201266
NCBI Official Name:
solute carrier family 39 (metal ion transporter), member 11
NCBI Official Symbol:
SLC39A11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW89107
Protein GI Number:
119609513
Purification:
ZIP11 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
This antibody will not cross-react with the zinc transporter ZIP10.
Swissprot #:
Q8N1S5
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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