KCTD15 Antibody
| Code | Size | Price |
|---|
| PSI-5085-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5085-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
KCTD15 Antibody: Potassium channel tetramerization domain-containing protein 15
Application Note:
KCTD15 antibody can be used for detection of KCTD15 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
KCTD15 Antibody: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.
Background References:
- Hill JO. Genetic and environmental contributions to obesity. Am. J. Clin. Nutr.1998; 68:991-2.
- Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat. Genetics2009; 41:25-34.
- Renstrom F, Payne F, Nordstrom A, et al. Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Human. Mol. Gen.2009; 18:1489-96.
Buffer:
KCTD15 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
KCTD15 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human KCTD15.
The immunogen is located within the last 50 amino acids of KCTD15.
The immunogen is located within the last 50 amino acids of KCTD15.
NCBI Gene ID #:
79047
NCBI Official Name:
potassium channel tetramerisation domain containing 15
NCBI Official Symbol:
KCTD15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q96SI1
Protein GI Number:
74732704
Purification:
KCTD15 Antibody is affinity chromatography purified via peptide column.
Research Area:
Obesity
Swissprot #:
Q96SI1
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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