PTER Antibody
| Code | Size | Price |
|---|
| PSI-5173-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5173-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
PTER Antibody: HPHRP, RPR-1, Phosphotriesterase-related protein, Parathion hydrolase-related protein, hPHRP
Application Note:
PTER antibody can be used for detection of PTER by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.
Background References:
- Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82.
- Alimova-Kost MV, Imreh S, Buchman VL, et al. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet.. Cell Genet.1998; 83:16-7.
- Meyre D, Delplanque J, Chevre JC, et al. Genome-wide associated study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet.2009; 41:157-9.
Buffer:
PTER Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (88%)
Immunogen:
PTER antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PTER.
The immunogen is located within amino acids 250 - 300 of PTER.
The immunogen is located within amino acids 250 - 300 of PTER.
NCBI Gene ID #:
9317
NCBI Official Name:
phosphotriesterase related
NCBI Official Symbol:
PTER
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
CAH73146
Protein GI Number:
55664514
Purification:
PTER Antibody is affinity chromatography purified via peptide column.
Research Area:
Obesity
Swissprot #:
Q96BW5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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