ZBED3 Antibody
| Code | Size | Price |
|---|
| PSI-5123-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5123-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ZBED3 Antibody: Zinc finger BED domain-containing protein 3, Axin-interacting protein
Application Note:
ZBED3 antibody can be used for detection of ZBED3 by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
Background References:
- Chen T, Li M, Ding Y, et al. Identification of Zinc-finger BED domain containing 3 (Zbed3) as a novel axin-interacting protein that activates Wnt/b-catenin signaling. J. Biol. Chem.2009; 284:6683-9.
Buffer:
ZBED3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZBED3 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ZBED3.
The immunogen is located within the first 50 amino acids of ZBED3.
The immunogen is located within the first 50 amino acids of ZBED3.
NCBI Gene ID #:
84327
NCBI Official Name:
zinc finger, BED-type containing 3
NCBI Official Symbol:
ZBED3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 26 kDa
Observed: 28 kDa
Observed: 28 kDa
Protein Accession #:
NP_115743
Protein GI Number:
14150185
Purification:
ZBED3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
Swissprot #:
Q96IU2
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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