ZCRB1 Antibody
| Code | Size | Price |
|---|
| PSI-5225-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5225-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ZCRB1 Antibody: MADP1, RBM36, MADP-1, SNRNP31, ZCCHC19, Zinc finger CCHC-type and RNA-binding motif-containing protein 1
Application Note:
ZCRB1 antibody can be used for detection of ZCRB1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
ZCRB1 Antibody: ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
Background References:
- Wang H, Gao MX, Li L, et al. Isolation, expression, and characterization of the human ZCRB1 gene mapped to 12q2. Genomics2007; 89:59-69.
- Trivedi AK, Bararia D, Christopeit M, et al. Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination. Oncogene2007; 1789-801.
- Will CL, Schneider C, Hossbach M, et al. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA2004; 10:929-41.
Buffer:
ZCRB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
ZCRB1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZCRB1.
The immunogen is located within the last 50 amino acids of ZCRB1.
The immunogen is located within the last 50 amino acids of ZCRB1.
NCBI Gene ID #:
85437
NCBI Official Name:
zinc finger CCHC-type and RNA binding motif 1
NCBI Official Symbol:
ZCRB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_149105
Protein GI Number:
51243065
Purification:
ZCRB1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q8TBF4
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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