TMEM214 Antibody
| Code | Size | Price |
|---|
| PSI-5297-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5297-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM214 Antibody: Transmembrane protein 214
Application Note:
TMEM214 antibody can be used for detection of TMEM214 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
TMEM214 Antibody: Transmembrane protein 214 (TMEM214) is a 77kD membrane protein which is widely expressed at high level. The gene encoding this protein maps to chromosome 2, at 2p23.3 TMEM214 interacts with LSM1, an SM-like protein, forming a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. The detailed function of TMEM214 is still unknown, but a recent study showed that TMEM214 may be used to explore the contribution of human host factors of some infectious diseases such as Dengue fever, West Nile fever and yellow fever. Multiple isoforms of TMEM214 are known to exist.
Background References:
- Wan D, Gong Y, Qin W, et al. Large-scale cDNA transfection screening for genes related to cancer development and progression. Proc. Natl. Acad. Sci. U S A2004;101:15724-9.
- Lehner B and Sanderson CM. A protein interaction framework for human mRNA degradation. Genome Res.2004; 14:1315-23.
- Sessions OM, Barrows NJ, Souza-Neto JA, et al. Discovery of insect and human dengue virus host factors. Nature2009; 458:1047-50.
Buffer:
TMEM214 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen:
TMEM214 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TMEM214.
The immunogen is located within amino acids 70 - 120 of TMEM214.
The immunogen is located within amino acids 70 - 120 of TMEM214.
NCBI Gene ID #:
54867
NCBI Official Name:
transmembrane protein 214
NCBI Official Symbol:
TMEM214
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_060197
Protein GI Number:
134152721
Purification:
TMEM214 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q6NUQ4
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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