PGCC1 Antibody
| Code | Size | Price |
|---|
| PSI-5309-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5309-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
PGCC1 Antibody: CCPG, PGCC1, KIAA1838, dJ894D12.1, CCPG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, PPARG constitutive coactivator 1, Constitutive coactivator of PPAR-gamma
Application Note:
PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Background:
PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
Background References:
- Berger J and Moller DE. The mechanisms of actions of PPARs. Annu. Rev. Med.2002; 53:409-35.
- Li D, Kang Q, and Wang D-M. Constitutive coactivator of peroxisome proliferator-activated receptor (PPARg), a novel coactivator of PPARg that promotes adipogenesis. Mol. Endocrin.2007; 21:2320-33.
- Holden S and Raymond FL. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Gene2003; 318:149-61.
Buffer:
PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (92%)
Immunogen:
PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1.
The immunogen is located within the last 50 amino acids of PGCC1.
The immunogen is located within the last 50 amino acids of PGCC1.
NCBI Gene ID #:
84498
NCBI Official Name:
family with sequence similarity 120B
NCBI Official Symbol:
FAM120B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q96EK7
Protein GI Number:
74751843
Purification:
PGCC1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
This antibody will not cross-react with FAM120A.
Swissprot #:
Q96EK7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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