JMJD7 Antibody

ProSci
Product Code: PSI-5385
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5385-0.02mg0.02mg£150.00
Quantity:
PSI-5385-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of JMJD7 in 3T3 cell lysate with JMJD7 antibody at 1 μg/mL.
2 / 3
Immunohistochemistry of JMJD7 in rat liver tissue with JMJD7 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of JMJD7 in rat liver tissue with JMJD7 antibody at 20 μg/mL.

Western blot analysis of JMJD7 in 3T3 cell lysate with JMJD7 antibody at 1 μg/mL.
Immunohistochemistry of JMJD7 in rat liver tissue with JMJD7 antibody at 2.5 μg/mL.
Immunofluorescence of JMJD7 in rat liver tissue with JMJD7 antibody at 20 μg/mL.

Further Information

Additional Names:
JMJD7 Antibody: JmjC domain-containing protein 7, Jumonji domain-containing protein 7
Application Note:
JMJD7 antibody can be used for detection of JMJD7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
JMJD7 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD7 has not been identified. JMJD7 was initially thought to be a novel splice form of the phospholipase PLA2G4B which is located downstream of JMJD7 as most tissues express a read-through transcript of the two genes.
Background References:
  • Takeuchi T, Watanabe Y, Takano-Shimizu T, et al. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev. Dyn.2006; 235:2449-59.
  • Clissold PM and Ponting CP. JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2beta. Trends Biochem.Sci. 2001; 26:7-9.
Buffer:
JMJD7 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
JMJD7 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human JMJD7.

The immunogen is located within amino acids 230 - 280 of JMJD7.
NCBI Gene ID #:
100137047
NCBI Official Name:
jumonji domain containing 7
NCBI Official Symbol:
JMJD7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P0C870
Protein GI Number:
205783894
Purification:
JMJD7 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
P0C870
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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