OCIAD2 Antibody
| Code | Size | Price |
|---|
| PSI-5463-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5463-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
OCIAD2 Antibody: OCIA domain-containing protein 2, Ovarian carcinoma immunoreactive antigen-like protein
Application Note:
OCIAD2 antibody can be used for detection of OCIAD2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunoflourescence starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
OCIAD2 Antibody: OCIAD2 was identified by its sequence similarity with OCIAD1, and together OCIAD1 and OCIAD2 form the OCIA domain family. OCIAD2 mRNA was found to be expressed at higher levels in invasive adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component (BAC) of the lung. Loss of OCIAD2 expression was significantly correlated with lymphatic invasion, blood vessel invasion, and lymph node metastasis, indicating that OCIAD2 may play a role in cell adhesion and prevention of cell migration. While the function of OCIAD2 is still unknown, its expression in adenocarcinoma with BAC component is significantly associated with a favorable prognosis and may serve as a marker for selecting tumors that are treatable by limited surgery.
Background References:
- Strausberg RL, Feingold EA, Grouse LH, et al. Mammalian gene collection program team. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.
- Ishiyama T, Kano J, Anami Y, et al. OCIA domain containing 2 is highly expressed in adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component and is associated with better prognosis. Cancer Sci.2006; 98:50-7.
Buffer:
OCIAD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (71%), Bovine: (72%)
Immunogen:
OCIAD2 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human OCIAD2.
The immunogen is located within the last 50 amino acids of OCIAD2.
The immunogen is located within the last 50 amino acids of OCIAD2.
NCBI Gene ID #:
132299
NCBI Official Name:
OCIA domain containing 2
NCBI Official Symbol:
OCIAD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001014446
Protein GI Number:
62244044
Purification:
OCIAD2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer
Swissprot #:
Q56VL3
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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