FRMPD3 Antibody
| Code | Size | Price |
|---|
| PSI-5457-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5457-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
FRMPD3 Antibody: KIAA1817, FERM and PDZ domain-containing protein 3
Application Note:
FRMPD3 antibody can be used for detection of FRMPD3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
FRMPD3 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. Unlike other members of the FRMPD family, FRMPD3 has no known function. It is most similar to FRMPD4, which is highly expressed in multiple regions of the brain and enriched in the postsynaptic density (PSD) fractions, it is possible that FRMPD3 also interacts with other PDZ domain-containing proteins in neural cells.
Background References:
- An N, Blumer JB, Bernard ML. The PDZ and Band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins. J. Biol. Chem.2008; 283:24718-28.
- Stenzel N, Fetzer CP, Heumann R, et al. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. J. Cell Sci.2009; 122:3374-84.
- Lee HW, Choi J, Shin H, et al. Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis. J. Neurosci.2008; 28:14546-56.
Buffer:
FRMPD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FRMPD3 antibody was raised against an 18 amino acid synthetic peptide from near the center of human FRMPD3.
The immunogen is located within amino acids 690 - 740 of FRMPD3.
The immunogen is located within amino acids 690 - 740 of FRMPD3.
NCBI Gene ID #:
84443
NCBI Official Name:
FERM and PDZ domain containing 3
NCBI Official Symbol:
FRMPD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q5JV73
Protein GI Number:
118582027
Purification:
FRMPD3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
Q5JV73
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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