FAM59B Antibody
| Code | Size | Price |
|---|
| PSI-5481-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5481-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
FAM59B Antibody: FAM59B, FAM59B, KIAA2038, HRIHFB2063, GRB2-associated and regulator of MAPK protein-like, GRB2-associated and regulator of MAPK1-like
Application Note:
FAM59B antibody can be used for detection of FAM59B by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
FAM59B Antibody: FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
Background References:
- Blagoev B, Ong SE, Kratchmarova I, et al. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat. Biotechnol.2004; 22:1139-45.
- Tashiro K, Tsunematsu T, Okubo H, et al. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through activation of extracellular signal-regulated kinase signaling. J. Biol. Chem.2009; 284:20206-14.
Buffer:
FAM59B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FAM59B antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAM59B.
The immunogen is located within amino acids 600 - 650 of FAM59B.
The immunogen is located within amino acids 600 - 650 of FAM59B.
NCBI Gene ID #:
150946
NCBI Official Name:
family with sequence similarity 59, member B
NCBI Official Symbol:
FAM59B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q75VX8
Protein GI Number:
190359325
Purification:
FAM59B Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q75VX8
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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