INCA1 Antibody
| Code | Size | Price |
|---|
| PSI-5531-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5531-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
Family with sequence similarity 212 member A, INKA1, C3orf54
Application Note:
FAM212A antibody can be used for detection of FAM212A by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2).
Background References:
- Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.
- Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.
Buffer:
FAM212A antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FAM212A antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FAM212A.
The immunogen is located within the last 50 amino acids of FAM212A.
The immunogen is located within the last 50 amino acids of FAM212A.
NCBI Gene ID #:
389119
NCBI Official Name:
Family with sequence similarity 212 member A
NCBI Official Symbol:
FAM212A
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 32 kDa
Observed: 33 kDa
Observed: 33 kDa
Protein Accession #:
NP_976248
Protein GI Number:
42766424
Purification:
FAM212A antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell,Neuroscience
SPECIFICITY:
FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.
Swissprot #:
Q96EL1
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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