SLFN14 Antibody
| Code | Size | Price |
|---|
| PSI-5543-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5543-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SLFN14 Antibody: Schlafen family member 14
Application Note:
SLFN14 antibody can be used for detection of SLFN14 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
SLFN14 Antibody: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. SLFN14 is a recently identified member of the SLFN family; its role has yet to be determined.
Background References:
- Schwarz DA, Katamaya CD, and Hedrick SM. Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity1998; 9:657-68.
- Bustos O, Naik S, Ayers G, et al. Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence. Gene2009; 447:1-11.
Buffer:
SLFN14 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rabbit: (81%)
Immunogen:
SLFN14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus human SLFN14.
The immunogen is located within amino acids 730 - 780 of SLFN14.
The immunogen is located within amino acids 730 - 780 of SLFN14.
NCBI Gene ID #:
342618
NCBI Official Name:
schlafen family member 14
NCBI Official Symbol:
SLFN14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001123292
Protein GI Number:
193788705
Purification:
SLFN14 Antibody is affinity chromatography purified via peptide column.
Research Area:
Immunology
Swissprot #:
P0C7P3
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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