SYNGR2 Antibody

ProSci
Product Code: PSI-5565
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5565-0.02mg0.02mg£150.00
Quantity:
PSI-5565-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

1 / 3
Western blot analysis of SYNGR2 in human lung tissue lysate with SYNGR2 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunohistochemistry of SYNGR2 in rat brain tissue with SYNGR2 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of SYNGR2 in rat brain tissue with SYNGR2 antibody at 20 μg/mL.

Western blot analysis of SYNGR2 in human lung tissue lysate with SYNGR2 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of SYNGR2 in rat brain tissue with SYNGR2 antibody at 2.5 μg/mL.
Immunofluorescence of SYNGR2 in rat brain tissue with SYNGR2 antibody at 20 μg/mL.

Further Information

Additional Names:
SYNGR2 Antibody: Synaptogyrin-2, Cellugyrin
Application Note:
SYNGR2 antibody can be used for detection of SYNGR2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
SYNGR2 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. The exact function of SYNGR2 is unknown, but studies suggest that it may play a role in regulating membrane traffic in non-neuronal cells.
Background References:
  • Belizaire R, Komanduri C, Wooten K, et al. Characterization of synaptogyrin 3 as a new synaptic vesicle protein. J. Comp. Neurol.2004; 470:266-81.
  • Kedra D, Pan HQ, Seroussi E, et al. Characterization of the human synaptogyrin gene family. Hum. Genet.1998; 103:131-41.
Buffer:
SYNGR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SYNGR2 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human SYNGR2.

The immunogen is located within amino acids 30 - 80 of SYNGR2.
NCBI Gene ID #:
9144
NCBI Official Name:
synaptogyrin 2
NCBI Official Symbol:
SYNGR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
AAI05993
Protein GI Number:
77415432
Purification:
SYNGR2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
O43760
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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