SYNGR4 Antibody

ProSci
Product Code: PSI-5569
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5569-0.02mg0.02mg£150.00
Quantity:
PSI-5569-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of SYNGR4 in K562 cell lysate with SYNGR4 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunohistochemistry of SYNGR4 in rat brain tissue with SYNGR4 antibody at 5 μg/mL.
3 / 3
Immunofluorescence of SYNGR4 in rat brain tissue with SYNGR4 antibody at 20 μg/mL.

Western blot analysis of SYNGR4 in K562 cell lysate with SYNGR4 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of SYNGR4 in rat brain tissue with SYNGR4 antibody at 5 μg/mL.
Immunofluorescence of SYNGR4 in rat brain tissue with SYNGR4 antibody at 20 μg/mL.

Further Information

Additional Names:
SYNGR4 Antibody: Synaptogyrin-4
Application Note:
SYNGR4 antibody can be used for detection of SYNGR4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
SYNGR4 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. SYNGR3 is predominantly expressed in brain and placenta. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear.
Background References:
  • Belizaire R, Komanduri C, Wooten K, et al. Characterization of synaptogyrin 3 as a new synaptic vesicle protein. J. Comp. Neurol.2004; 470:266-81.
  • Kedra D, Pan HQ, Seroussi E, et al. Characterization of the human synaptogyrin gene family. Hum. Genet.1998; 103:131-41.
Buffer:
SYNGR4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SYNGR4 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human SYNGR4.

The immunogen is located within amino acids 30 - 80 of SYNGR4.
NCBI Gene ID #:
23546
NCBI Official Name:
synaptogyrin 4
NCBI Official Symbol:
SYNGR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
CAA09754
Protein GI Number:
4128019
Purification:
SYNGR4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
O95473
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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