NAT11 Antibody
| Code | Size | Price |
|---|
| PSI-5549-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5549-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
NAT11 Antibody: NAT11, PATT1, NAT11, N-alpha-acetyltransferase 40, N-acetyltransferase 11
Application Note:
NAT11 antibody can be used for detection of NAT11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
NAT11 Antibody: N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE). Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.
Background References:
- Arnesen T, Van Damme P, Polevoda B, et al. Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proc. Natl. Acad. Sci. USA2009; 106:8157-62.
- OK Song, Wang X, Waterborg JH, et al. An Nalpha-acetyl-transferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J. Biol. Chem.2003; 278:38109-1
Buffer:
NAT11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NAT11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NAT11.
The immunogen is located within the last 50 amino acids of NAT11.
The immunogen is located within the last 50 amino acids of NAT11.
NCBI Gene ID #:
79829
NCBI Official Name:
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
NCBI Official Symbol:
NAA40
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_079047
Protein GI Number:
189571650
Purification:
NAT11 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q86UY6
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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