RSRC1 Antibody
| Code | Size | Price |
|---|
| PSI-5607-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5607-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
RSRC1 Antibody: BM-011, SFRS21, SRrp53, SRRP53, BM-011SRrp53
Application Note:
RSRC1 antibody can be used for detection of RSRC1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
RSRC1 Antibody: The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
Background References:
- Cazalla D, Newton K, and Caceres JF. A noel SR-related protein is required for the second step of pre-mRNA splicing. Mol. Cell. Biol.2005; 25:2969-80.
- Potkin SG, Turner JA, Fallon JA, et al. Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. Mol. Psych.2009; 14:416-28.
- Zhang QH, Ye M, Wu XY, et al. Cloning and functional analysis of cDNAs with open reading frames for 300 previously unidentified genes expressed in CD34+ hematopoietic stem/progenitor cells. Genome Res./i> 2008; 18:640-3.
Buffer:
RSRC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
RSRC1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RSRC1.
The immunogen is located within the last 50 amino acids of RSRC1.
The immunogen is located within the last 50 amino acids of RSRC1.
NCBI Gene ID #:
51319
NCBI Official Name:
arginine/serine-rich coiled-coil 1
NCBI Official Symbol:
RSRC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_057709
Protein GI Number:
38488727
Purification:
RSRC1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
Swissprot #:
Q96IZ7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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