LZTR1 Antibody
| Code | Size | Price |
|---|
| PSI-5621-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5621-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
LZTR1 Antibody: BTBD29, LZTR-1, SWNTS2, TCFL2, Leucine-zipper-like transcriptional regulator 1
Application Note:
LZTR1 antibody can be used for detection of LZTR1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
LZTR1 Antibody: LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
Background References:
- Kurahashi H, Akagi K, Inazawa J, et al. Isolation and characterization of a novel gene deleted in DiGeorge syndrome. Hum. Mol. Genet.1995; 4:541-9.
- Nacak TG, Leptien K, Fellner D, et al. The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis. J. Biol. Chem.2006; 281:5065-71.
Buffer:
LZTR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
LZTR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human LZTR1.
The immunogen is located within amino acids 130 - 180 of LZTR1.
The immunogen is located within amino acids 130 - 180 of LZTR1.
NCBI Gene ID #:
8216
NCBI Official Name:
leucine-zipper-like transcription regulator 1
NCBI Official Symbol:
LZTR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
CAJ86451
Protein GI Number:
90403050
Purification:
LZTR1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q8N653
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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