BCAS4 Antibody
| Code | Size | Price |
|---|
| PSI-5631-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5631-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
BCAS4 Antibody: CNOL, Breast carcinoma-amplified sequence 4
Application Note:
BCAS4 antibody can be used for detection of BCAS4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
BCAS4 Antibody: The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.
Background References:
- Barlund M, Monni O, Weaver JD, et al. Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo amplification, overexpression, and fusion in breast cancer. Genes Chromosomes Cancer2002; 35:311-7.
Buffer:
BCAS4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BCAS4 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human BCAS4.
The immunogen is located within the first 50 amino acids of BCAS4.
The immunogen is located within the first 50 amino acids of BCAS4.
NCBI Gene ID #:
55653
NCBI Official Name:
breast carcinoma amplified sequence 4
NCBI Official Symbol:
BCAS4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
CAI23006
Protein GI Number:
56203146
Purification:
BCAS4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q8TDM0
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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