CAZIP Antibody
| Code | Size | Price |
|---|
| PSI-5639-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5639-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
CAZIP Antibody: ICIS, CAZIP, TIP150, KIAA0774, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Tracking protein of 150 kDa
Application Note:
CAZIP antibody can be used for detection of CAZIP by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
Background References:
- Du Puy L, Beqqali A, Monshouwer-Kloots J, et al. CAZIP, a novel protein expressed in the developing heart and nervous system. Dev. Dyn.2009; 238:2903-11.
- Jiang K, Wang J, Liu J, et al. TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep.2009; 10:857-65.
Buffer:
CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CAZIP antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human CAZIP.
The immunogen is located within amino acids 1300 - 1350 of CAZIP.
The immunogen is located within amino acids 1300 - 1350 of CAZIP.
NCBI Gene ID #:
23281
NCBI Official Name:
microtubule associated tumor suppressor candidate 2
NCBI Official Symbol:
MTUS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001028774
Protein GI Number:
140161498
Purification:
CAZIP Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q5JR59
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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