Slc37A2 Antibody
| Code | Size | Price |
|---|
| PSI-5647-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5647-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
Slc37A2 Antibody: pp11662, SPX2, Sugar phosphate exchanger 2, Solute carrier family 37 member 2
Application Note:
Slc37A2 antibody can be used for detection of Slc37A2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
Slc37A2 Antibody: The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.
Background References:
- Bartolini L and Antonarakis SE. The human sugar-phosphate/phosphate exchanger family SLC37. Eur. J. Physiol.2004; 447-780-3.
- Kim JY, Tillison K, Zhou S, et al. The major facilitator superfamily member Slc37a2 is a novel macrophage-specific gene selectively expressed in obese white adipose tissue. Am. J. Physiol. Endocrinol. Metab.2007; 293:E110-20.
Buffer:
Slc37A2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Slc37A2 antibody was raised against a 15 amino acid synthetic peptide near the center of human Slc37A2.
The immunogen is located within amino acids 230 - 280 of Slc37A2.
The immunogen is located within amino acids 230 - 280 of Slc37A2.
NCBI Gene ID #:
219855
NCBI Official Name:
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
NCBI Official Symbol:
SLC37A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_938018
Protein GI Number:
38093649
Purification:
Slc37A2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Obesity
Swissprot #:
Q8TED4
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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