LYRM1 Antibody
| Code | Size | Price |
|---|
| PSI-5659-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5659-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
LYRM1 Antibody: A211C6.1, LYR motif-containing protein 1
Application Note:
LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
LYRM1 Antibody: LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.
Background References:
- Qiu J, Ni YH, Gong HX, et al. Identification of differentially expressed genes in omental adipose tissues of obese patients by suppression subtractive hybridization. Biochem. Biophys. Res. Comm.2007; 352:469-78.
- Qiu J, Gao CL, Zhang M, et al. LYRM1, a novel gene promotes proliferation and inhibits apoptosis of preadipocytes. Eur. J. Endocrinol.2009; 160:177-84.
Buffer:
LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1.
The immunogen is located within the first 50 amino acids of LYRM1.
The immunogen is located within the first 50 amino acids of LYRM1.
NCBI Gene ID #:
57149
NCBI Official Name:
LYR motif containing 1
NCBI Official Symbol:
LYRM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW66844
Protein GI Number:
119587248
Purification:
LYRM1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Obesity
Swissprot #:
O43325
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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