LYRM2 Antibody

ProSci
Product Code: PSI-5661
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5661-0.02mg0.02mg£150.00
Quantity:
PSI-5661-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

1 / 3
Western blot analysis of LYRM2 in A549 cell lysate with LYRM2 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunocytochemistry of LYRM2 in A549 cells with LYRM2 antibody at 20 μg/mL.
3 / 3
Immunofluorescence of LYRM2 in A549 cells with LYRM2 antibody at 20 μg/mL.

Western blot analysis of LYRM2 in A549 cell lysate with LYRM2 antibody at (A) 1 and (B) 2 μg/mL.
Immunocytochemistry of LYRM2 in A549 cells with LYRM2 antibody at 20 μg/mL.
Immunofluorescence of LYRM2 in A549 cells with LYRM2 antibody at 20 μg/mL.

Further Information

Additional Names:
LYRM2 Antibody: DJ122O8.2, LYR motif-containing protein 2
Application Note:
LYRM2 antibody can be used for detection of LYRM2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
LYRM2 Antibody: The Lyr motif found in the LYR-motif containing protein family is similar to that found in the sacchromyces cerevisiae protein ISD11, an iron-sulfur protein in the mitochondria that is thought to play a role in iron homeostasis. No known function has been assigned to LYRM2, although LYRM1 is thought to be involved in preadipocyte progression and LYRM3 has been suggested to be a candidate gene for the branchio-oto-renal (BOR) syndrome.
Background References:
  • Shi Y, Ghosh MC, Tong WH, et al. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Hum. Mol. Genet.2009; 18:3014-25.
  • Qiu J, Gao CL, Zhang M, et al. LYRM1, a novel gene promotes proliferation and inhibits apoptosis of preadipocytes. Eur. J. Endocrinol.2009; 160:177-84.
  • Lin X, Wells DE, Kimberling WJ, et al. Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q1 Hum. Heredity1999; 49:75-80.
Buffer:
LYRM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen:
LYRM2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human LYRM2.

The immunogen is located within the last 50 amino acids of LYRM2.
NCBI Gene ID #:
57226
NCBI Official Name:
LYR motif containing 2
NCBI Official Symbol:
LYRM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_065199
Protein GI Number:
10092689
Purification:
LYRM2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q9NU23
User NOte:
Optimal dilutions for each application to be determined by the researcher.

Related Products

Product NameProduct CodeSupplier 
LYRM2 PeptidePSI-5661PProSci Summary Details