ZC3H12C Antibody
| Code | Size | Price |
|---|
| PSI-5677-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5677-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ZC3H12C Antibody: MCPIP3, KIAA1726, MCPIP3, Probable ribonuclease ZC3H12C, MCP-induced protein 3
Application Note:
ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
ZC3H12C Antibody: ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.
Background References:
- Zhou L, Azfer A, Niu J, et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ. Res.2006; 98:1177-85.
- Liang J, Wang J, Azfer A, et al. A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. J. Biol. Chem.2008; 283:6337-46.
Buffer:
ZC3H12C Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZC3H12C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12C.
The immunogen is located within the first 50 amino acids of ZC3H12C.
The immunogen is located within the first 50 amino acids of ZC3H12C.
NCBI Gene ID #:
85463
NCBI Official Name:
zinc finger CCCH-type containing 12C
NCBI Official Symbol:
ZC3H12C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_203748
Protein GI Number:
148886668
Purification:
ZC3H12C Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
Q9C0D7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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