ZC3H12D Antibody
| Code | Size | Price |
|---|
| PSI-5679-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5679-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ZC3H12D Antibody: TFL, p34, MCPIP4, C6orf95, dJ281H8.1, TFL, Probable ribonuclease ZC3H12D, MCP-induced protein 4
Application Note:
ZC3H12D antibody can be used for detection of ZC3H12D by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
ZC3H12D Antibody: ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
Background References:
- Zhou L, Azfer A, Niu J, et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ. Res.2006; 98:1177-85.
- Liang J, Wang J, Azfer A, et al. A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. J. Biol. Chem.2008; 283:6337-46.
Buffer:
ZC3H12D Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZC3H12D antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZC3H12D.
The immunogen is located within amino acids 280 - 330 of ZC3H12D.
The immunogen is located within amino acids 280 - 330 of ZC3H12D.
NCBI Gene ID #:
340152
NCBI Official Name:
zinc finger CCCH-type containing 12D
NCBI Official Symbol:
ZC3H12D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 58 kDa
Observed: 57 kDa
Observed: 57 kDa
Protein Accession #:
EAW47801
Protein GI Number:
119568186
Purification:
ZC3H12D Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
A2A288
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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