TMEM184A Antibody
| Code | Size | Price |
|---|
| PSI-5681-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5681-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM184A Antibody: Transmembrane protein 184A
Application Note:
TMEM184A antibody can be used for detection of TMEM184A by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
TMEM184A Antibody: TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.
Background References:
- Svingen T, Beverdam A, Bernard P, et al. Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation. Reproduction2007; 133:983-9.
- Svingen T, Wilhelm D, Combes AN, et al. Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis. Dev Dyn.2009; 238:956-64.
Buffer:
TMEM184A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (80%)
Immunogen:
TMEM184A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human TMEM184A.
The immunogen is located within the last 50 amino acids of TMEM184A.
The immunogen is located within the last 50 amino acids of TMEM184A.
NCBI Gene ID #:
202915
NCBI Official Name:
transmembrane protein 184A
NCBI Official Symbol:
TMEM184A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 45 kDa
Observed: 52 kDa
Observed: 52 kDa
Protein Accession #:
NP_001091089
Protein GI Number:
148276981
Purification:
TMEM184A Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q6ZMB5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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