TMEM184B Antibody
| Code | Size | Price |
|---|
| PSI-5683-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5683-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM184B Antibody: FM08, HS5O6A, C22orf5, PSEC0108, Transmembrane protein 184B, Putative MAPK-activating protein FM08
Application Note:
TMEM184B antibody can be used for detection of TMEM184B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
Background References:
- Matsuda A, Suzuki Y, Honda G, et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene2003; 22:3307-18.
- Dunham I, Shimizu N, Roe BA, et al. The DNA sequence of human chromosome 2. Nature1999; 402:489-495.
Buffer:
TMEM184B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
TMEM184B antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184B.
The immunogen is located within the last 50 amino acids of TMEM184B.
The immunogen is located within the last 50 amino acids of TMEM184B.
NCBI Gene ID #:
25829
NCBI Official Name:
transmembrane protein 184B
NCBI Official Symbol:
TMEM184B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_036396
Protein GI Number:
63259329
Purification:
TMEM184B Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q9Y519
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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