ENC-1 Antibody
| Code | Size | Price |
|---|
| PSI-5693-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5693-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Isotype: IgY
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ENC-1 Antibody: NRPB, CCL28, ENC-1, PIG10, KLHL35, KLHL37, TP53I10, NRPB, Ectoderm-neural cortex protein 1, Kelch-like protein 37
Application Note:
ENC-1 antibody can be used for detection of ENC-1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
ENC-1 Antibody: The ectoderm-neural cortex-1 (ENC-1) protein is an early and highly specific marker of neural induction in vertebrates. It is a kelch family related protein that functions as an actin-binding protein and has been suggested to be involved in the organization of the actin cytoskeleton during neural fate specification and development of the nervous system. ENC-1 has also been shown to be required for adipocyte differentiation when cytoskeletal reorganization and cell shape change from fibroblastic preadipocytes to spherical adipocytes occur.
Background References:
- Hernandez MC, Andres-Barquin PJ, Martinez S, et al. ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J. Neurosci.1997; 17:3038-51.
- Zhao L, Gregoire F and Sul HS. Transient induction of ENC-1, a Kelch-related actin-binding protein, is required for adipocyte differentiation. J. Biol. Chem.2000; 275:16845-50.
Buffer:
ENC-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ENC-1 antibody was raised against a 13 amino acid synthetic peptide near the center of human ENC-1.
The immunogen is located within amino acids 230 - 280 of ENC-1.
The immunogen is located within amino acids 230 - 280 of ENC-1.
NCBI Gene ID #:
8507
NCBI Official Name:
ectodermal-neural cortex 1 (with BTB-like domain)
NCBI Official Symbol:
ENC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
O14682
Protein GI Number:
12644050
Purification:
ENC-1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
O14682
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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