TINP1 Antibody

ProSci
Product Code: PSI-5705
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5705-0.02mg0.02mg£150.00
Quantity:
PSI-5705-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Isotype: IgY
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

1 / 2
Western blot analysis of TINP1 in rat brain tissue lysate with TINP1 antibody at (A) 1 and (B) 2 μg/mL.
2 / 2
Immunohistochemistry of TINP1 in human brain tissue with TINP1 antibody at 5 μg/mL.

Western blot analysis of TINP1 in rat brain tissue lysate with TINP1 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of TINP1 in human brain tissue with TINP1 antibody at 5 μg/mL.

Further Information

Additional Names:
TINP1 Antibody: HCLG1, TINP1, CDK105, HCL-G1, HUSSY29, HUSSY-29, Ribosome biogenesis protein NSA2 homolog, Hairy cell leukemia protein 1
Application Note:
TINP1 antibody can be used for detection of TINP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
TINP1 Antibody: TINP1 (TGF-beta inducible nuclear protein 1), also known as NSA2 (Nop seven-associated 2), is a highly conserved nucleolar protein essential for large ribosomal subunit biogenesis. NSA2 is broadly expressed in human tissues and cultured cell lines, and located in the nucleolus of the cell. It is thought to be involved in cell proliferation and cell cycle regulation.
Background References:
  • Lebreton A, Saveanu C, Decourty L, et al. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J. Biol. Chem.2006; 281:27099-108.
  • Zhang H, Ma X, Shi T, et al. NSA2, a novel nucleolus protein regulates cell proliferation and cell cycle. Biochem. Biophys. Res. Commun.2010; 391:651-8.
Buffer:
TINP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
TINP1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human TINP1.

The immunogen is located within the last 50 amino acids of TINP1.
NCBI Gene ID #:
10412
NCBI Official Name:
NSA2 ribosome biogenesis homolog (S. cerevisiae)
NCBI Official Symbol:
NSA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_055701
Protein GI Number:
7662677
Purification:
TINP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
O95478
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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